Design and development of high shear mixers Fundamentals

Processing & Engineering | Liquid Mixing: Solid Challenges

Pharmaceutical processing & engineering: Liquid mixing and blending would seem to be among the most straightforward of pharmaceutical manufacturing unit operations. Mechanical process mixers have been on the market for more than 100 years, and not much separates mixers for drug making from those used in food and chemical industries.

PDF Emulsion Processing - Homogenization

A Small Design Change with a Large Effect • In addition to pressure changes leading to cavitation, fluid jets also impinge in a mixing chamber • Extremely turbulent flow situation and very high shear forces cause additional disruption of droplets • Higher homogenization pressures possible

Taylor‐Couette reactor: Principles, design, and

Feb 03,  · To increase the shear stress instead, Forney et al. proposed the rotor design depicted in Figure 7. 66 This design deliberately creates cavitation at very high rotational speeds to achieve high shear forces. The high degree of shear originating inside the reactor leads to small bubble sizes within the reactor as consequence, which increase mass

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National Oilwell Varco, L.P. P.O. Box 1123 Dayton, Ohio 45401 tel: 1-800-643-0641 fax: 1-937-454-3379 [email protected]

Manufacture of Shampoos - US - Industrial High Shear Mixers

These problems can be overcome by the use of a Silverson High Shear mixer, typically an In-Line mixer added to the existing process. Batch mixers and the Silverson Flashmix powder/liquid mixing system can also be used. Operation is as follows: Stage 1. The vessel is charged with water. The in-tank agitator and In-Line mixer are started, and the

PDF Guide to Design Criteria for Bolted and Riveted Joints

4.5 Reuse of High-Strength Bolts, 62 4.6 Galvanized Bolts and Nuts, 63 4.7 Use of Washers, 65 4.8 Corrosion and Embrittlement, 66 4.9 Effect of Nut Strength, 69 4.10 Basis for Design Recommendations, 70 4.10.1 Bolts Subjected to Tension, 70 4.10.2 Bolts Subjected to Shear, 71 4.10.3 Bolts Subjected to Combined Tension and Shear, 71 5.

Understanding High Viscosity Mixing to Achieve Uniformity

The mixing process is generally performed to achieve homogenous blending of two or more ingredients as uniformity can influence the performance, durability, stability, reaction and other factors of the resultant product. Some of the major factors to be considered for achieving uniformity include the mixer design, the times and techniques of

Ultra-High Performance Concrete UHPC: Fundamentals

Ultra-High Performance Concrete UHPC: Fundamentals, Design, Examples. First Edition. de-icing salt 62 design, for bending and normal force 72 design for shear tests 75 - Delft University of Technology 81-84 - RWTH Aachen University 79-81 - the University of Kassel 75-79 - typical example of development of strains 47 fibre

New High-Shear Mixer Design - PCI Mag

Multiple agitator designs -- high-speed disperser and rotor-stator. It is ideal for laboratory development work for batches up to 5 gallons. The mixer can be mounted on an existing laboratory bench top, or on a stand-alone bench. Call 800/243.ROSS or e-mail [email protected]

PDF] Scale-up of batch rotor–stator mixers. Part 1—power

Abstract Rotor–stator mixers are characterized by a set of rotors moving at high speed surrounded closely by a set of stationary stators which produces high local energy dissipation. Rotor–stator mixers are therefore widely used in the process industries including the manufacture of many food, cosmetic and health care products, fine chemicals, and pharmaceuticals.

Engineer's Standpoint: History of Reinforced Concrete Design

Jul 10,  · Design of Prestressed Concrete by Arthur H. Nilson, 2nd edition -1987; Reinforced Concrete Fundamentals by P. Ferguson, J. Breen, J. Jirsa, 5th edition-1988; Reinforced Concrete Design by C. K. Wang and C. G. Salmon, 6th edition-1998; Building Design and Construction Handbook by Frederick S. Merritt and Jonathan T. Ricketts, 6th edition -2002.

PDF HIGH-SHEAR MIXING Don't Fall Victim to Common Misconceptions

high-shear mixing to the next level, CE, April 2004, pp. 24-26. FIGURE 1. A ver-satile lab-scale high-shear mixer (HSM) is typically equipped with attachments that enable it to oper-ate as a batch mixer, inline mixer, or high-speed "saw tooth" disperser HIGH-SHEAR MIXING Don't Fall Victim to Common Misconceptions During the scaleup of

Faculty | Mechanical Engineering

New product design. Design of machine components and systems. The influence of designer personality and environment on design outcomes. Engineering Management - with a particular interest in product development. Lean product design. Interaction of business, product, and process in engineering systems. Products design for flexible manufacturing

Canaan Pharmaceutical Equipment Manufacturer

Established in 2000 Zhejiang Canaan Technology Limited is the only A-share listed company in solid dosage equipment field in China who focuses on research and development, production and sales of pharmaceutical equipment. At present, Canaan has evolved into a leading pharmaceutical equipment manufacturer. Canaan Manufacturing Research Institute.

Single-Pass Emulsification Processes in Two Different

Single-pass continuous emulsifications were studied in kerosene- and silicone oil-aqueous systems with two inline high shear mixers (HSMs) adopting two main commercial configurations, including the dual-row ultrafine-toothed and the single-row blade-screen units. The effects of the processing parameters on the measured drop sizes and power consumptions were investigated.

Mixer Selection for Paints and ... - High Speed Dispersers

Once considered state of the art in high shear mixing technology, the HSD (high-speed disperser) is a familiar sight in plants across the country. But these days it plays a minor role on most process lines. It is seldom capable of more than pre-mixing (inclusion), and it generally cannot produce what we accept as a “colloidal dispersion” today.

The Art of Mixing: High-Speed Dispersers

The High-Speed Disperser (HSD) is the basic tool used by all paint, ink, chemical, plastic and adhesive manufacturers. Although a very simple device, the HSD is often misused or misapplied. The following outlines the basic design parameters of an HSD. Normal operating viscosity range = 1,000 - 25,000 cps and up to 50,000 cps max.

Bioprocess Equipment for biotech & pharmaceutical industries

Bioprocess Equipment for biotech and pharmaceutical industries. Steridose specializes in the design, development and manufacturing of magnetic coupled mixers and radial diaphragm valves. Proven Expertise. Specialized Products. Bioprocess Equipment with more than 40 years of mixing expertise. Steridose is a manufacturer of bioprocess equipment

ECA Granulation

Fundamentals – high shear granulation High shear granulation is a popular granulation method. It is a robust granulation technique capable of handling most APIs, to produce granules of intermediate densi-ties, between roller compacted and fluid bed processed granules. Operationally, control of the shear energy input for granulation is by

PDF 7.9 Design Guidelines - Rock Riprap 7.9.1 Rock Riprap

and/or ice impacts, or the cumulative effect of high shear stresses and forces from wind and/or boat generated waves. The stability factor is used to increase the design rock size when these conditions must be considered. Table 7-7 presents guidelines for the selection of an appropriate value for the stability factor.

Lightnin | SPX Flow

Lightnin draws upon over 95 years' worth of highly-focused industry knowledge and a relentless desire to innovate. SPX FLOW's Lightnin brand has been recognized as the leader in Mixing Technology. Our extensive knowledgebase and dedication to continuous product development ensure efficient and reliable plant operations around the world.

Fundamentals of Bulk Solids Mixing and Blending - Chemical

Sep 01,  · Fundamentals of Bulk Solids Mixing and Blending. Mixing and blending of bulk solids is a common processing step in many industries. For example, in pharmaceutical manufacturing of solid dosage formulations (tablets or capsules), small amounts of a powdered active drug are carefully blended with excipients, such as sugar, starch, cellulose

Base Plate and Anchor Rod Design - Portada

2 / design guide 1, 2nd edition / base plate and anchor rod design The vast majority of building columns are designed for axial compression only with little or no uplift.

Design, Modeling, and Fabrication of High-Speed VCSEL with

We have studied the characteristics of frequency response at 850-nm GaAs high-speed vertical-cavity surface-emitting lasers (VCSELs) with different kinds of oxide aperture sizes and cavity length using the PICS3D simulation program. Using 5-μm oxide aperture sizes, the frequency response behavior can be improved from 18.4 GHz and 15.5 GHz to 21.2 GHz and 19 GHz in a maximum of 3 dB at 25 °C

PDF ACI mix design - Memphis

ACI Mix Design Here are some examples of different measures of slump: ACI Mix Design The flowchart is a representation of the principal properties of ACI mix design of concrete workability - slump water and air content w/c ratio cement coarse aggregate fine aggregate moisture adjustment trial mix CIVL 1112 ACI Mix Design 3/10

Single-Use Processing for Microbial FermentationBioProcess

Apr 14,  · The goal is to optimize performance by maintaining equilibrium between energy and cost efficiency (Figure 1). Achieving a proper balance requires maintaining k L a, agitation, and gas flow rate within modest limits as defined roughly by the enclosed area in the upper‑right segment of the figure.Extreme conditions lead to foaming, high cost, shear damage, oxygen limitations, poor mixing,